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Milad Arabi ooghry

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Greetings! This message is as vibrant as a bubbling chemical reaction.
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I want to share a few memories with you.
There was a time I was tasked with optimizing a high-performance liquid chromatography (HPLC) method for a new drug candidate. The goal was to separate enantiomers with baseline resolution, but the column kept giving inconsistent retention times. I tweaked mobile phase compositions, adjusted flow rates, and recalibrated the UV detector, referencing GLP standards to ensure compliance. Hours turned into days as I pored over chromatograms, trying to pinpoint the issue—maybe column degradation or an unnoticed pH shift? The challenge was exhausting, but we eventually nailed the method by switching to a chiral stationary phase, achieving perfect separation just in time for the validation study.
I’ll never forget the time I tried to impress my professor with a flashy demo using a Grignard reagent in organic synthesis. Picture me, confidently mixing phenylmagnesium bromide in a dry fl
@ooghry
ooghry / optuna_xgboost.py
Created May 25, 2022 12:39
xgboost#7941
# -*- coding: utf-8 -*-
import numpy as np
import numpy
import pandas as pd
import optuna
import sklearn.datasets
import sklearn.metrics
from sklearn.model_selection import train_test_split
import xgboost as xgb
[root@tse msgpack-2.1.0]# zts-phpize
Configuring for:
PHP Api Version: 20170718
Zend Module Api No: 20170718
Zend Extension Api No: 320170718
[root@tse msgpack-2.1.0]# ./configure
checking for grep that handles long lines and -e... /usr/bin/grep
checking for egrep... /usr/bin/grep -E
checking for a sed that does not truncate output... /usr/bin/sed
checking for cc... cc